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4 Weeks of Alternate-Day Fasting Aids Weight Loss, but Reduces Muscle

Rubenhair Latvia
2 min read
22.12.2025
4 Weeks of Alternate-Day Fasting Aids Weight Loss, but Reduces Muscle

**The Effects of Alternate-Day Fasting on Weight Loss** Researchers have found that alternate-day fasting can be an effective way to reduce body mass and fat mass, but it may also lead to a loss of muscle mass.

**The Effects of Alternate-Day Fasting on Weight Loss**

Researchers have found that alternate-day fasting can be an effective way to reduce body mass and fat mass, but it may also lead to a loss of muscle mass.

A recent study published in the journal Nutrients examined the effects of a 4-week alternate-day fasting protocol on a group of Asian males. The results showed significant reductions in body mass and fat mass, but also a decrease in muscle mass, even among participants who took protein supplements.

The researchers emphasized that while alternate-day fasting can be an effective weight loss strategy, it is essential to maintain daily exercise habits to prevent muscle loss. This type of eating plan works by reducing overall calorie intake, leading to weight loss and potentially muscle loss as well.

**Key Findings**
  • Alternate-day fasting resulted in significant reductions in body mass and fat mass.
  • The regimen also led to a loss of muscle mass, even among participants who took protein supplements.
  • Daily exercise is crucial when following an alternate-day fasting protocol to prevent muscle loss.
**Expert Insights**

Dr. Dana Hunnes, a senior clinical dietitian at UCLA Health, noted that the results were not surprising, as a calorie deficit can lead to weight loss and muscle loss. Dr. Mir Ali, a general surgeon and bariatric surgeon, emphasized the importance of understanding the nuances of weight loss programs and the potential risks associated with alternate-day fasting.

**Study Details**

The study involved two groups of Asian males, ages 21-35, who were assigned to a 4-week alternate-day fasting protocol. The participants fasted every other day, consuming only water or zero-calorie beverages while eating one small meal (400-600 calories) on non-fasting days. Some participants in the second group received a protein supplement to determine its effect on muscle mass loss.

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